Losartan (Cozaar)
ATI-format individual drug card with NCLEX-focused assessment, safety, teaching, and source attribution.
Losartan (Cozaar)
ATI class: ARB / Angiotensin II receptor blocker
Action
- Blocks angiotensin II receptor effects so vessels relax and aldosterone effect decreases.
Therapeutic use
- Hypertension
- Kidney protection in selected clients
- Heart failure support when ordered
Nursing assessment
- Monitor blood pressure, potassium, creatinine, pregnancy status, and angioedema symptoms.
Administration
- Verify route against the order and source table.
Side effects
- Dizziness
- Fatigue
Adverse effects
- Hyperkalemia
- Hypotension
- Angioedema
- Kidney function decline
Interactions
- Potassium supplements
- Salt substitutes
- Potassium-sparing diuretics
- NSAIDs
- Lithium
Contraindications
- Pregnancy
- Hypersensitivity
Precautions
- Use caution with renal artery stenosis, kidney disease, and volume depletion.
Client teaching
- Avoid potassium salt substitutes unless approved.
- Report facial/lip/tongue swelling, pregnancy, fainting, or low urine output.
Medication outcomes
- Therapeutic response with no priority adverse effects.
Antidote / rescue
- No specific antidote is seeded; hold/question unsafe doses and manage toxicity per provider, facility, or poison-control guidance.
NCLEX priority cues
- Pregnancy is a hard stop for ACE/ARB teaching.
- Angioedema is an airway priority.
- Potassium must be monitored.
Medication classes
Source attribution
Related study cards
Shows the medication class, ATI cues, source references, and connected study cards for this drug.
Reduces angiotensin effect so vessels relax and aldosterone-driven sodium and water retention decreases.
ATI medication adverse effect concept.
ATI medication nclex priority cue concept.
ATI medication class concept.
ATI medication class concept.
ATI medication client teaching concept.
ATI medication mechanism of action concept.
ATI medication side effect concept.
ATI medication side effect concept.
ATI medication therapeutic use concept.
ATI medication adverse effect concept.
ATI medication contraindication concept.