Labs and Abnormal Value Interpretation

Review the high-yield NCLEX lab values from the session compiler with low/high findings and priority nursing actions.

Lab interpretation table

Study ranges are broad references. Use school and facility ranges for exams and clinical work.

needs review
LabNormal rangeMeaningLow / high cluesPriority actions
Sodium135-145 mEq/LWater balance and neurologic status.
Sodium swells or shrinks the brain.
Low: Confusion, Headache, Seizures
High: Thirst, Dry mucosa, Restlessness
Institute seizure precautions for severe symptoms. Trend correction rate as ordered.
Potassium3.5-5.0 mEq/LCardiac conduction and muscle function.
K kills.
Low: Weakness, U waves, Constipation
High: Peaked T waves, Weakness, Cardiac arrest risk
Place symptomatic or critical abnormal values on cardiac monitor. Never IV push potassium.
Calcium8.5-10.5 mg/dLBone, clotting, neuromuscular excitability, and cardiac conduction.
Low calcium is twitchy; high calcium is slow and stony.
Low: Tetany, Tingling, Seizures
High: Kidney stones, Constipation, Confusion
Watch airway spasm/seizures when low. Promote hydration and safety when high if allowed.
Magnesium1.7-2.2 mg/dLNeuromuscular calming and cardiac rhythm stability.
Magnesium calms; too much shuts down.
Low: Tremors, Seizures, Torsades risk
High: Absent reflexes, Respiratory depression, Hypotension
Monitor reflexes and respirations during magnesium infusion. Keep calcium gluconate available when ordered.
BUN / CreatinineBUN 10-20 mg/dL; creatinine about 0.6-1.3 mg/dLKidney perfusion and filtration trends.
Creatinine is kidney filter trend.
High: Dehydration, AKI/CKD, Medication dosing risk
Trend urine output and nephrotoxic medication risk. Escalate rising creatinine with low urine output.
WBC4,500-11,000/mm3Infection, inflammation, marrow response, or immunosuppression.
Low: Neutropenia infection risk
High: Infection/inflammation, Stress response
Use neutropenic precautions when indicated. Trend with fever and cultures.
Hgb / HctHgb about 12-18 g/dL; Hct about 36-54%Oxygen-carrying capacity and bleeding/anemia trend.
Low: Fatigue, Dyspnea, Bleeding/anemia
High: Dehydration or polycythemia concern
Assess active bleeding and oxygenation. Trend after GI bleed, trauma, or surgery.
Platelets150,000-400,000/mm3Primary clot formation.
Low: Bruising, Petechiae, Bleeding
High: Clot risk in selected contexts
Bleeding precautions when low. Avoid IM injections if severely low per policy.
PT / INRPT about 11-13.5 sec; INR about 0.8-1.1 unless anticoagulatedExtrinsic clotting pathway; warfarin monitoring context.
Warfarin watches PT/INR.
High: Bleeding risk, Liver dysfunction, Warfarin effect
Assess bleeding and medication safety. Know vitamin K reversal context for warfarin.
aPTTAbout 25-35 sec unless anticoagulatedIntrinsic clotting pathway; heparin monitoring context.
Heparin has two Ps in aPTT.
High: Bleeding risk, Heparin effect
Assess bleeding with heparin therapy. Know protamine reversal context for heparin.
GlucoseFasting about 70-99 mg/dLImmediate brain fuel and diabetes control.
Low: Sweaty, Shaky, Confused, Seizure
High: Polyuria, Thirst, DKA/HHS risk
Treat symptomatic hypoglycemia promptly. Check ketones/acid-base when DKA suspected.
Albumin3.5-5.0 g/dLProtein/nutrition status and oncotic pressure.
Low: Edema, Poor wound healing, Ascites risk
Assess nutrition, liver disease, kidney loss, and wound risk.
AmmoniaVaries by lab; commonly about 15-45 mcg/dLLiver detoxification and encephalopathy trend.
Ammonia clouds the brain.
High: Confusion, Asterixis, Lethargy
Assess airway/safety and lactulose response when ordered.
TroponinLab-specific; normally very low/undetectableMyocardial injury marker.
High: MI/ACS concern, Other myocardial strain/injury contexts
Pair with symptoms and ECG. Escalate chest pain plus elevated/rising value.
BNPLab-specific; often <100 pg/mL used as a low-risk referenceHeart stretch and heart failure support marker.
High: Heart failure exacerbation context, Volume/pressure overload
Assess dyspnea, edema, weight, and lung sounds with the value.
ABG pH7.35-7.45Overall acid-base direction.
Low: Acidosis
High: Alkalosis
Use pH first to decide acid versus alkalotic state.
PaCO235-45 mm HgRespiratory acid controlled by ventilation.
CO2 equals respiratory.
Low: Respiratory alkalosis direction
High: Respiratory acidosis direction
Assess ventilation, airway, and breathing when PaCO2 drives the problem.
HCO322-26 mEq/LMetabolic base controlled mainly by kidneys.
HCO3 equals metabolic.
Low: Metabolic acidosis direction
High: Metabolic alkalosis direction
Look for DKA, renal failure, GI losses, or vomiting based on direction.