Hydrochlorothiazide

ATI-format individual drug card with NCLEX-focused assessment, safety, teaching, and source attribution.

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CardiacRenal / Urinary / Electrolytesneeds review

Hydrochlorothiazide

ATI class: Thiazide diuretic

Action

  • Promotes sodium and water excretion in the distal tubule.

Therapeutic use

  • Hypertension
  • Mild edema

Nursing assessment

  • Monitor blood pressure, potassium, sodium, glucose, uric acid, kidney function, weight, and dizziness.

Administration

  • Verify route against the order and source table.

Side effects

  • Dizziness
  • Photosensitivity
  • Increased urination

Adverse effects

  • Hypokalemia
  • Hyponatremia
  • Hyperglycemia
  • Hyperuricemia
  • Dehydration

Interactions

  • Digoxin
  • Lithium
  • Antihypertensives
  • NSAIDs
  • Corticosteroids

Contraindications

  • Anuria

Precautions

  • Use caution with gout, diabetes, kidney disease, older adults, and sulfonamide allergy history.

Client teaching

  • Rise slowly.
  • Report muscle weakness, palpitations, severe dizziness, or gout flare.
  • Use sun protection if photosensitive.

Medication outcomes

  • Therapeutic response with no priority adverse effects.

Antidote / rescue

  • No specific antidote is seeded; hold/question unsafe doses and manage toxicity per provider, facility, or poison-control guidance.

NCLEX priority cues

  • Hypokalemia is the classic thiazide safety cue.
  • Gout and glucose can worsen.
  • Do not ignore dizziness in older adults.

Medication classes

Diuretics

Source attribution

Engage_MedTable_Hydrochlorothiazide (1).pdf
ati-pdf
Google Drive source topic: Diuretics / Hypertension
google-drive
Sentinel pharmacology API reference
sentinel-api
Manual ATI-format NCLEX normalization
manual-seed

Related study cards

Shows the medication class, ATI cues, source references, and connected study cards for this drug.

12 study links
Med classmedication class
Diuretics

Moves fluid out through the kidneys; the exact electrolyte effect depends on the class.

ATI cueInteraction
Antihypertensives

ATI medication interaction concept.

ATI cueContraindication
Anuria

ATI medication contraindication concept.

ATI cueInteraction
Corticosteroids

ATI medication interaction concept.

ATI cueAdverse Effect
Dehydration

ATI medication adverse effect concept.

ATI cueInteraction
Digoxin

ATI medication interaction concept.

ATI cueSide Effect
Dizziness

ATI medication side effect concept.

ATI cueNCLEX Priority Cue
Do not ignore dizziness in older adults.

ATI medication nclex priority cue concept.

ATI cueNCLEX Priority Cue
Gout and glucose can worsen.

ATI medication nclex priority cue concept.

ATI cueAdverse Effect
Hyperglycemia

ATI medication adverse effect concept.

ATI cueTherapeutic Use
Hypertension

ATI medication therapeutic use concept.

ATI cueAdverse Effect
Hyperuricemia

ATI medication adverse effect concept.