Famotidine (Pepcid)
ATI-format individual drug card with NCLEX-focused assessment, safety, teaching, and source attribution.
Famotidine (Pepcid)
ATI class: H2 receptor antagonist / GI acid reducer
Action
- Blocks H2 receptors in stomach parietal cells to decrease gastric acid secretion.
Therapeutic use
- GERD
- Peptic ulcer disease
- Heartburn
- Stress ulcer prophylaxis when ordered
Nursing assessment
- Assess abdominal pain, reflux symptoms, GI bleeding cues, and response to therapy.
- Review renal function because dose adjustment may be needed.
- Monitor older adults for confusion or CNS effects.
Administration
- PO
- IV
Side effects
- Headache
- Dizziness
- Constipation
- Diarrhea
Adverse effects
- Confusion in older adults or renal impairment
- Dysrhythmias with rapid IV administration
- Hypersensitivity
Interactions
- Drugs needing acidic gastric pH for absorption
- Other acid suppressants when duplicated
Contraindications
- Hypersensitivity
Precautions
- Use caution with kidney impairment and older adult confusion risk.
Client teaching
- Report black stools, vomiting blood, trouble swallowing, or unintentional weight loss.
- Do not use OTC acid reducers long term without provider guidance.
- Avoid trigger foods if they worsen reflux.
Medication outcomes
- Reduced heartburn/reflux symptoms
- Ulcer healing support
- Reduced gastric acid secretion
Antidote / rescue
- No specific antidote is seeded; overdose care is supportive.
NCLEX priority cues
- GI bleeding cues outrank routine heartburn teaching.
- Renal impairment increases dose-review importance.
- Confusion in an older adult can be medication related.
Medication classes
Source attribution
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Reduces stomach acid so irritated tissue can heal and reflux symptoms decrease.
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